Cell-Free DNA Extraction Kits: Compare & Buy cfDNA Isolation Kits

The cost of cfDNA collection tubes and extraction kits varies by supplier and pack size. The OncoSeek cfDNA Extraction Kit from Cambrian Bioworks is available in 50-reaction packs with pricing available on request. Tester kits are also available upon request, allowing labs to evaluate performance before purchase. Contact Cambrian Bioworks directly for a quote.

The OncoSeek cfDNA Extraction Kit is optimized for plasma samples. Plasma is the preferred matrix for cfDNA isolation in liquid biopsy workflows, as it minimizes genomic DNA contamination from lysed blood cells. As little as 1 mL of plasma is sufficient to achieve high cfDNA yields, including low-abundance circulating tumor DNA fragments.

Extracted cfDNA from the OncoSeek Kit is validated for use in next-generation sequencing (NGS) library preparation, quantitative PCR (qPCR), and digital PCR (ddPCR). It is also suitable for minimal residual disease (MRD) detection, mutation profiling, ctDNA analysis, and longitudinal monitoring of treatment response in oncology research workflows.

Yes. The OncoSeek cfDNA Extraction Kit's bead-based purification method supports automation, reducing manual handling steps and enabling high-throughput processing. Cambrian Bioworks also offers the Beluga automated liquid handler, which is designed to streamline nucleic acid extraction workflows regardless of sample load or batch size.

The OncoSeek Kit employs selective binding conditions that preferentially capture short cfDNA fragments (150–200 bp) while limiting co-purification of high-molecular-weight genomic DNA. This results in minimal gDNA contamination, which is critical for sensitive downstream applications such as ddPCR and NGS that can be confounded by gDNA background.

The OncoSeek cfDNA Extraction Kit is currently designated For Research Use Only (RUO) and is intended for oncology research and liquid biopsy development applications. Cambrian Bioworks holds ISO 13485 certification and CE-IVD mark for clinical DNA extraction products. For regulatory status specific to diagnostic use in your region, contact Cambrian Bioworks directly.