Molecular Diagnostics Extraction Kits: cfDNA, FFPE & Blood RNA Solutions

Molecular diagnostics typically includes sample preparation, nucleic acid extraction, purification, quality control, and downstream analysis. These kits cover the extraction stage for cfDNA, RNA, and gDNA from plasma, FFPE tissue, and blood. They support applications such as mutation profiling, gene expression studies, fusion detection, biomarker discovery, and oncology research workflows.

Three widely used molecular diagnostic techniques are PCR-based testing, sequencing-based analysis such as NGS, and hybridization or expression-based assays. The extraction kits in this category are designed to produce nucleic acids suitable for these workflows, including qPCR, ddPCR, RNA-seq, mutation analysis, transcriptomics, and biomarker studies from challenging sample types.

This category includes kits for plasma cfDNA, FFPE tissue RNA, FFPE tissue gDNA, whole blood RNA, and whole blood gDNA. Several products also support related laboratory inputs such as cell cultures or mixed sample workflows on automated platforms. This range helps labs standardize extraction across oncology, molecular diagnostics, and translational research applications.

Yes. Multiple kits are designed for automation and are compatible with Cambrian Bioworks' Manta platform. Automation-friendly formats, pre-filled cartridges, and magnetic bead-based purification help reduce hands-on time, improve reproducibility, and support flexible throughput. This is especially useful for labs handling variable sample volumes or scaling from single samples to larger runs.

Depending on the kit, extracted nucleic acids are suitable for NGS, PCR, qPCR, ddPCR, RNA sequencing, microarrays, mutation analysis, transcriptome studies, and biomarker discovery. The cfDNA kit is optimized for liquid biopsy workflows, while the FFPE and blood RNA kits support expression profiling, fusion detection, and transcriptomics. gDNA kits support sequencing and genetic testing workflows.

Regulatory status varies by product. Some kits are designated RUO, especially for oncology research and FFPE RNA workflows, while others are described for research and clinical diagnostic laboratory use. Cambrian Bioworks also holds ISO 13485 certification and CE-IVD credentials at the company level. Labs should confirm the intended use and validation requirements for their specific workflow before implementation.