Automated Molecular Diagnostic Systems for Clinical Nucleic Acid Extraction

Processing times vary by kit, but the workflows are designed for rapid turnaround. Whole blood gDNA and FFPE gDNA extraction can be completed in about 28 minutes after lysis, while whole blood RNA extraction has a 50-minute on-deck time. These shorter automated runs help reduce hands-on work and support faster reporting in clinical and translational laboratory settings.

The available workflows cover both RNA and genomic DNA extraction. Cambrian offers a whole blood RNA isolation kit as well as whole blood gDNA and FFPE gDNA isolation kits. This allows laboratories to support a range of downstream molecular applications, including RNA sequencing, gene expression studies, PCR assays, NGS, microarrays, mutation analysis, and oncology-focused testing.

Yes. The systems are positioned for research and clinical diagnostic use in laboratory environments, and Cambrian Bioworks holds ISO 13485 certification for medical device quality management. The company also has CE-IVD marking for clinical DNA extraction and CDSCO IVD certification. Labs should still confirm workflow fit, intended use, and local regulatory requirements for their specific testing programs.

The workflows use pre-filled, non-reusable cartridges, which help minimize manual reagent handling and reduce cross-contamination risk between samples. For RNA extraction, the kit includes RNase free DNase to reduce DNA contamination in sensitive assays. Cambrian also recommends following the Manta sterilization protocol to maintain workflow integrity and consistent performance in routine laboratory use.

Extracted nucleic acids are suitable for a broad range of downstream applications. These include PCR-based assays, next-generation sequencing, microarray analysis, RNA-Seq, transcriptome analysis, mutation analysis, biomarker discovery, and oncology studies. Product data also cites use in infectious disease testing, reproductive genetics, blood cancer monitoring, and translational research workflows requiring reproducible nucleic acid quality.

Yes. The cartridge-based design supports flexible throughput, including single-sample processing, so labs do not need to wait for large batches before running extraction. Whole blood gDNA and FFPE gDNA workflows support 1 to 32 samples per run, which is useful for clinical labs balancing urgent cases, variable daily volumes, and efficient use of consumables and instrument time.