Bone Marrow RNA Extraction Kits for Hematology & Oncology Research

Yes. These kits are positioned for applications including cancer research, biomarker discovery, transcriptome analysis, gene expression profiling, and BCR-ABL testing and monitoring. High RNA integrity values, DNase inclusion, and magnetic bead-based purification make them well suited for research and molecular diagnostic workflows where sample quality and reproducibility are critical.

The Cambrian Blood RNA Isolation Kit supports whole blood input volumes from 500 µL to 2 mL. This range allows labs to scale extraction based on sample availability and assay requirements. Reported RNA yield increases with input volume, helping researchers optimize recovery for downstream workflows such as sequencing, transcriptomics, and expression analysis.

Extracted RNA can support RNA sequencing, transcriptome analysis, gene expression profiling, epigenetic studies, biomarker discovery, and oncology-focused molecular assays. The kit’s reported RNA Integrity Number range of 8.6 to 9.7 indicates suitability for sensitive workflows where intact RNA is important for reliable library preparation, expression measurement, and analytical consistency.

Magnetic bead-based extraction is designed to deliver higher RNA recovery and cleaner extracts than traditional spin-column methods. It also supports automation more effectively, which can reduce manual handling and improve reproducibility across runs. For labs processing multiple oncology or hematology samples, this approach can help streamline workflows while maintaining RNA quality for downstream analysis.

The listed on-deck workflow time is 50 minutes, with a lysis time of 40 minutes on the Manta platform. This automated format helps reduce hands-on labor compared with manual methods. For research and diagnostic laboratories, a defined runtime can improve planning, support throughput goals, and make RNA extraction easier to standardize across operators and batches.

The kit includes RNase free DNase and 10X DNase buffer to help minimize DNA contamination during RNA purification. This is especially important for downstream applications such as RNA-Seq, transcriptome analysis, and gene expression studies, where residual DNA can affect data quality. The non-reusable cartridge design also helps reduce cross-contamination risk between samples.