RNA Extraction Systems: Automated Platforms for Blood & Tissue Samples

The point of RNA extraction is to isolate intact, clean RNA so laboratories can accurately study gene expression, transcriptomes, biomarkers, and disease-related molecular changes. High-quality RNA is essential for applications such as RNA sequencing, fusion detection, immune profiling, and molecular diagnostics. Reliable extraction also improves reproducibility and confidence in downstream analytical results.

The products in this category support whole blood and FFPE tissue workflows. The Cambrian Blood RNA Isolation Kit is designed for whole blood inputs from 500 µL to 2 mL, while the Cambrian FFPE RNA Isolation Kit is optimized for formalin-fixed paraffin-embedded tissue, including small tissue curl inputs. This makes the category relevant for both clinical and translational research settings.

Automated RNA extraction helps reduce hands-on labor, improve reproducibility, and support higher-throughput laboratory operations. These systems use magnetic bead-based purification and automation-friendly formats to standardize processing across samples. Features such as pre-filled cartridges, same-day FFPE workflows, and defined on-deck times can help labs streamline operations while maintaining RNA quality for sensitive downstream assays.

Yes. The kits are positioned for applications including RNA-seq, transcriptome analysis, gene expression profiling, biomarker discovery, and fusion detection. The blood RNA kit reports RNA integrity numbers of 8.6 to 9.7, while the FFPE kit is optimized for challenging archived tissue with DV200 above 70%. These attributes support workflows where RNA quality and consistency are important.

DNA contamination is addressed through integrated or included DNase treatment. The blood RNA kit includes RNase-free DNase and buffer, while the FFPE RNA kit specifies integrated DNase treatment with zero DNA contamination noted in product information. This is important for expression profiling, biomarker studies, and other RNA-based analyses where residual DNA can interfere with assay accuracy and interpretation.

Yes. Both products are designed with automation in mind and align well with high-throughput laboratory environments. The blood RNA kit runs on the Manta platform with a 50-minute on-deck time and pre-filled cartridges, while the FFPE kit is automation-friendly and compatible with Manta and 96-well format systems. These features help labs scale processing without sacrificing workflow consistency.