Illumina FFPE DNA Prep & Exome Sequencing: DNA Extraction Requirements

After the lysis step, the Manta-based automated workflow completes gDNA isolation in just 28 minutes. The pre-filled cartridge system minimises manual intervention — simply peel the seal, add the lysate, and the Manta instrument handles the rest, significantly reducing hands-on time in busy diagnostic labs.

The kit supports a flexible throughput of 1 to 32 samples in a single run. Importantly, distinct sample types can be processed simultaneously, making it highly efficient for oncology labs that handle limited or heterogeneous FFPE specimens without the need for batching.

Yes. The high-molecular-weight gDNA produced by the Cambrian FFPE gDNA Isolation Kit meets the input quality requirements for Illumina FFPE DNA Prep and exome sequencing protocols. The magnetic bead technology minimises fragmentation and contamination, which are critical quality factors for successful library preparation.

The Cambrian FFPE gDNA Isolation Kit is designed for use with the Manta cartridge-based automated nucleic acid extraction system by Cambrian Bioworks. Manta's compact design fits inside a laboratory hood and features a touchscreen interface, UVC contamination control, and remote monitoring capability.

The product is backed by Cambrian Bioworks' ISO 13485 quality management certification and CE-IVD mark under EU Regulation 2017/746 (IVDR). The company also holds CDSCO IVD certification (MFG/IVD/2025/000069), confirming compliance for clinical diagnostic use in India and regulated markets.

Cambrian Bioworks provides a downloadable Instructions for Use (IFU) document, the Manta Playbook workflow guidance resource, and a comprehensive FAQ covering FFPE block age effects, decrosslinking, and paraffin wax removal. Demo scheduling and direct technical support are also available via cambrianbioworks.com.