DNA Rapid Extraction Kits: Speed vs Quality — Comparing Options

The Cambrian Whole Blood gDNA and FFPE gDNA Isolation Kits complete processing in just 28 minutes after lysis. The OncoSeek cfDNA Extraction Kit takes approximately 55 minutes. All workflows are automated using the Manta cartridge-based system, minimizing hands-on time significantly.

The Whole Blood gDNA kit delivers yields of 6–15 ng/µL with A260/280 ratios of 1.8–2.0 and A260/230 ratios of 2.0–2.2, suitable for sensitive downstream applications. The OncoSeek cfDNA kit achieves 5–20× higher cfDNA yield compared to leading competitors using just 1 mL of plasma.

Yes. All three kits are validated for Next-Generation Sequencing (NGS) and PCR-based assays. The OncoSeek cfDNA kit is additionally optimized for digital PCR (ddPCR) and qPCR. DNA extracted using these kits is also compatible with microarray analysis and mutation profiling workflows.

Cambrian Bioworks holds ISO 13485 certification for quality management in medical device manufacturing and a CE-IVD mark under EU Regulation 2017/746 (IVDR). The company also holds CDSCO IVD certification (MFG/IVD/2025/000069) and an IVD certification from the Government of Karnataka, India.

Yes. The pre-filled, single-use cartridge system is designed for flexible throughput from 1 to 32 samples per run. Each cartridge contains only what is needed for one sample, eliminating buffer and plastic waste — reducing plastic consumption by up to 24% compared to conventional tube-based workflows.

Yes. The OncoSeek cfDNA Extraction Kit is specifically optimized for liquid biopsy applications. It preferentially captures 150–200 bp tumor-derived cfDNA fragments, enriching ctDNA with minimal genomic DNA contamination. It is validated for MRD detection, longitudinal treatment monitoring, early cancer detection research, and NGS library preparation.